Hi,

There might be conflicts with system shortcuts. There are also bugs, of course.

A solution is to redefine the shortcuts to whatever you want. To quickly test, use a scheme session. E.g. open one and then enter

 (kbd-map ("C-4" (make 'equation)))

and evaluate it. Remember that pressing enter in a scheme session by default evaluates the current input field. You'll have to press ctrl+enter or alt+enter depending on your config. Alternatively, activate "multiline input" in the options for the session. (first of the small group of three blue icons in the focus bar)

Search the scheme code (Shift+F1) for "kbd-map" to see many more examples.

Once you are happy with your definitions, just copy them to your my-init-texmacs.scm file. You might have to create it first. I don't know where it should be in Windows. Alternatively, activate the developer tools, and click on Developer->Open my-init-texmacs.scm

Good luck!